The Collaborative Study on the Genetics of Alcoholism (COGA) is a United States multi-center, family study that aims to identify genes that contribute to alcohol use disorders and related phenotypes (Begleiter et al., 1995). Since 2005, the adolescent and young adult study in COGA has used a longitudinal design to examine the development of substance use disorders in youth from high-risk (defined as recruited through alcohol dependent probands with multiple affected family members) and community comparison families. Members aged 12 to 22 were recruited from six sites across the US and interviewed approximately every two years with ongoing data collection. Detailed descriptions of the COGA prospective adolescent and young adult sample have been previously published (Chorlian et al., 2015; Dick et al., 2013).
