Despite temporal smearing and the inferior resolution to that obtained with time-domain analysis, the wavelet-based estimates suggest that event-related theta power peaked in the LT cortex at ∼320 ms (Figure 2), preceding the activity in the PFC and consistent with our previous observations (Marinkovic et al., 2003). ROI analysis indicated that the SW elicited stronger theta than PW in the left LT at this latency. This difference was also observed in the left ACC under placebo and it continued during the subsequent time window, ∼370–520 ms. Importance of the left temporal lobe in semantic functions has been confirmed in numerous studies. ERPs recorded intracranially from epilepsy patients offer a unique opportunity to examine the generators of the ERPs recorded on the scalp. Such studies confirm that the anteroventral temporal cortices are the main generators of the N400 (Halgren et al., 1994; Nobre et al., 1994), with word-specific potentials recorded in the LT areas as well (Halgren et al., 1994). Lesions of the left temporal lobe result in impaired semantic comprehension at the single-word level (Hart and Gordon, 1990; Dronkers et
