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Chunk #14 — Discussion

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CYP2A6 slow nicotine metabolism is associated with increased quitting by adolescent smokers.
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Overall, the findings herein reveal that in adolescence, genetically slow nicotine metabolizers are more likely to quit smoking than normal nicotine metabolizers. A greater understanding of the factors underpinning cessation in adolescence may improve quit rates early in the course of smoking onset, reducing subsequent long-term illnesses and mortality that result from cigarette smoking.