Chunk #16 — 3. Results — 3.2 Allelic Imbalance assay

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Evidence of allelic imbalance in the schizophrenia susceptibility gene ZNF804A in human dorsolateral prefrontal cortex.

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Genomic DNA from the DLPFC samples was genotyped for both the SZ risk SNP rs1344706 and the exonic SNP rs12476147. The LD between these two SNPs was calculated using PLINK, and pairwise LD analysis revealed substantial LD between the two SNPs (r2 = 0.343, D′ = 0.952) (Figure 1).