We also detected significant differences in cortical connectivity but in this case the pattern of age-related differences was reversed, with children showing significantly weaker connectivity between paralimbic, association, and limbic areas (Figure 4A). Graph-theoretical measures of degree, efficiency, and path length of the four cortical subdivisions did not differ between the two groups (Figure 3). This suggests that key aspects of cortico-cortical wiring are similar in children and young-adults but the strength of the connections is weaker in children.
