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Chunk #5 — Introduction — EEG Power and Coherence Abnormalities in Bipolar Disorder

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Resting state EEG power and coherence abnormalities in bipolar disorder and schizophrenia.
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Evidence for EEG abnormalities in BP is less well characterized than in SZ. With respect to spectral power, El Badri and colleagues found increased power at all frequencies (although markedly in the beta band) in BP relative to NC (El-Badri et al. 2001), whereas Başar and colleagues reported reduced alpha power in euthymic patients (Başar et al. 2012). Further, dysfunctional long-range connectivity appears to be more consistently observed in BP. For example, reduced long-range alpha coherence between frontal-temporal regions was found during rest in manic patients (Bhattacharya 2001), and in the beta band during rest in euthymic patients (Chen et al. 2008).