A total of 425 045 alcohol-induced deaths were identified from 2000 to 2016. In 2000, there were 19 627 deaths (14 979 [76.3%] men; 4649 [23.7%] women) in the US population from alcohol-induced causes, occurring at an age-standardized rate of 8.9 deaths per 100 000 residents (men: 14.4 deaths per 100 000 residents; women: 4.0 deaths per 100 000 residents) (Figure 1). By 2016, there were 34 857 deaths (25 213 [72.3%] men; 9644 [27.7%] women) with alcohol-induced causes at an age-standardized rate of 12.0 deaths per 100 000 residents (men: 17.9 deaths per 100 000 residents; women: 6.6 deaths per 100 000 residents). The age-standardized rates for each year from 2000 to 2016 by individually contributing cause of alcohol-induced death are presented in eFigure 1 in the Supplement. In 2016, alcoholic liver disease accounted for 15 148 of 25 213 alcohol-induced deaths (60.1%) among men and 6665 of 9644 (69.1%) among women. Deaths due to accidental poisoning by and exposure to alcohol or mental and behavioral disorders due to alcohol accounted for 9039 deaths (35.9%) among men and 2717
