find that in Chinese patients high neuroticism scores also predispose to higher comorbidity and scores correlate with disease severity. Previous research found that neuroticism accounted for a significant part of the lifetime comorbidity of common psychiatric disorders (internalizing disorders and externalizing disorders) and suggests neuroticism as a potential general underlying vulnerability factor for psychopathology (Clark et al., 1994; Khan et al., 2005; Krueger and Markon, 2001; Sher and Trull, 1994). As a cross sectional analysis, our results showed that elevated neuroticism scores were associated with lifetime comorbidity.