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Chunk #22 — Discussion

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Genome-wide linkage analyses of quantitative and categorical autism subphenotypes.
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recruited families from different clinical centers. Due to these arguments, we performed linkage analyses without the AGP site as a covariate (but with the adjustments for gender, verbal/nonverbal status, and age of ADI-R completion). Without the AGP site as a covariate, the heritability for SOC changed from .35 to .50 and from .52 to .62 for BEH. However, the linkage results did not change dramatically with the ranges of the differences between –.4 to .4 for SOC and between –.4 to .5 for BEH and the highest LOD scores changed from 1.84 to 1.68 for SOC and from 2.09 to 2.06 for BEH.