activity (quintiles), nonsteroidal anti-inflammatory drug (NSAID) use (yes/no), parental history of CHD before the age of 60 (yes/no), history of diabetes (yes/no) and hypertension (yes/no) at baseline, total:HDL-cholesterol ratio (quintiles), and hormone therapy among women (never, past, current). Baseline was defined as the year of blood draw. Lewontin's D prime (D') and the correlation coefficient (r2) were calculated as two measures of linkage disequilibrium (LD) between CRP polymorphisms among control participants. CRP levels were not normally distributed and were log-transformed for analyses. Multivariable linear regression analyses were conducted to model the association between CRP SNPs and CRP levels among control participants.
