paperKB
coga / coga-kb
Help
Sign in

Chunk #10 — Materials and Methods — Statistical Analyses

Source
Low frequency genetic variants in the μ-opioid receptor (OPRM1) affect risk for addiction to heroin and cocaine.
Embedded
yes

Text

Power analyses were carried out using QUANTO 1.2.4 assuming an unmatched case-control design, a population risk for addiction of 0.005, a log additive model and a 2 sided p-value of 0.05. For variants with a MAF of 0.5% we had 77% power to detect association in the EA population and 64% power in the AA population.