The intriguing hints provided by initial genetic studies may ultimately identify the neural origins of propensity to binge drink, which likely reflect fundamental individual differences to alcohol intake and interact with the wider context of personality or psychiatric variables. Searching for the primary reasons why some young adults binge would foster genetic links between binge drinking and subsequent alcohol dependence. Characterizing the association between binge-drinking mechanisms and the development of alcoholism could reveal a means to pursue and evaluate treatment interventions before the addictive disease is fully developed.