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Chunk #3 — Introduction

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Mapping the genetic architecture of gene expression in human liver.
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as a susceptibility gene for a novel type 1 diabetes (T1D) locus that was recently identified in a large-scale GWAS [14] and subsequently extensively replicated in a number of cohorts [15]. We also identify SORT1 and CELSR2 as candidate susceptibility genes for a locus recently associated with coronary artery disease [16] and plasma low-density lipoprotein (LDL)-cholesterol levels [17,18].