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Chunk #22 — DISCUSSION

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Distribution of disease-associated copy number variants across distinct disorders of cognitive development.
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so for autism and epilepsy. While schizophrenia stood out the most from ID, under broad criteria schizophrenia’s relationship with ID would be most consistent with a subsumed model as well. However, the schizophrenia specific CNVs should be interpreted with caution as some have been found thus far only in a single study. The interpretation of these findings suggests that ID may represent a disorder with the broadest possibilities of genetic mechanisms and susceptibility pathways, and the other disorders appear to have more restricted susceptibilities.