Differential gene expressions in various cell lines in the standard culture condition were analyzed using the NIA Array Analysis software (http://lgsun.grc.nia.nih.gov/ANOVA/) which implements ANOVA statistics with two additional methods to reduce the number of false positives: (1) small error variances were replaced with the average error variance estimated from 500 genes with similar signal intensity, and (2) false discovery rates (FDR<0.05) were used to select genes with differential expression, instead of p-values [69]. The FDR method accounts for the effect of multiple hypotheses testing.
