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Chunk #29 — DISCUSSION — Conclusions

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Familial association of abstinent remission from alcohol use disorder in first-degree relatives of alcohol-dependent treatment-seeking probands.
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The likelihood of abstinent remission was more than 3 times greater for individuals who were related to an abstinent proband versus those related to a proband with persistent AUD. Identifying characteristics that underpin this familiality, and whether it is entirely environmental, heritable, or a combination, is a challenge for future study.