Briefly, the Drug Targetor method,19 was used to assess the association of individual drug or small molecule related gene sets and to assess drug class enrichment. Gene sets are given in accompanying supplementary files (see key resources table). Analyses were run using MAGMA v1.1045 using gene flanks of −35kb 5′ and +10kb 3′.90 Drug class enrichment was calculated using area under the curve (AUC) defined by the % of drug class gene-sets vs their rank in all the gene-sets.91
