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Chunk #31 — 4. Discussion

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Genetic and environmental influences on cannabis use initiation and problematic use: a meta-analysis of twin studies.
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Genetic factors influencing cannabis use overlap with those influencing use of other illicit drugs, although there are also specific genetic factors influencing use of each particular drug (31, 48, 53–55). The general genetic vulnerability to drug use could be related genes underlying personality characteristics such as novelty seeking (56–59), to biochemical attributes (60), or to psychiatric vulnerability(61, 62).