(3%), which is the case for many other Asian countries such as China (∼4% of Chinese women aged 15 years or older are smokers [50]). Thus, we could not determine whether this gene cluster has any significant impact on smoking behaviors in Korean women. Finally, the number of informative SNPs genotyped within this region was limited. To have a better coverage for these samples, more SNPs with a high density are greatly needed for further analysis of this cluster in relation to smoking-related phenotypes.