Chunk #7 — Results — Array design and coverage estimates

Source

Smokescreen: a targeted genotyping array for addiction research.

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yes

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Quit Success Score12058 Literature search1329 Comorbidity markers Lung Cancer3091 Psychiatric disorders1200 Tobacco smoke constituent update and metabolic phenotypes1907 Pulmonary diseases and traits7945 Cardiovascular diseases and traits2247 General high-value markers Pharmacogenomic markers2030 NHGRI GWAS Catalog7612 eQTLs9736 Loss-of-function markers4680 Ancestry informative markers (AIMs)5545 HLA/KIR8894 Mitochondrial180Array Total646247 aMarkers in categories may overlapTable 2Counts of imputed SNPs (1000 Genomes Project: Phase 1, March 2012 release)YRIASNEURGenome-Wide MAF ≥ 0.011526343380914349213645 MAF ≥ 0.05921911259736096505846Addiction Genes MAF ≥ 0.01794696417902476661 MAF ≥ 0.05474408303991333356 CHRNA5, CHRNA3 and CHRNB4 MAF ≥ 0.01337723771922 MAF ≥ 0.05212118621519 CYP2A6 and CYP2B6 MAF ≥ 0.01288626792696 MAF ≥ 0.05215720432136