Chunk #27 — RESULTS — Differential expression of signaling proteins in calcium, cyclic nucleotide and small GTPase 2nd messenger pathways in PCPs — Ca2+ binding proteins

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Transcriptional Architecture of Synaptic Communication Delineates GABAergic Neuron Identity.

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Each PCP expresses a set of ~5–8 different Ca2+-binding proteins (CaBPs; Figure 5D, S5E), many of which are in fact signaling proteins (e.g. Rasgrp1 in CHCs). This result suggests that differential expression of multiple Ca2+ binding and signaling proteins might shape the spatiotemporal dynamics and specificity of Ca2+signaling among PCPs.