right pallidum—where the effect size is positive but very small (\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\triangle {R}^{2}$$\end{document}△R2 = 0.0005). Importantly, the largest regional association was less than half the size of the association between alcohol consumption and global GMV, indicating that the global reduction in GMV associated with alcohol intake results from aggregating smaller associations that are widespread across the brain (rather than constrained to specific areas).