A total of 5,390 subjects were aggregated from family-based and case-control genetic studies of DSM-IV OD and CD (American Psychiatric Association, 1994). Subjects were recruited at five sites: the University of Connecticut Health Center (n=2,224), Yale University School of Medicine (n=2,210), the University of Pennsylvania School of Medicine (n=477), McLean Hospital (n=258) and the Medical University of South Carolina (n=221). The institutional review board at each site approved the protocol and informed consent forms. The National Institute on Drug Abuse provided a Certificate of Confidentiality. Subjects were paid for their participation.
