Alcohol use was assessed with the daily record of standard drinks obtained by the Timeline Followback Interview24 with a drinking diary as a memory guide, and validated by weekly breathalyzer determinations, monthly GGT values and collateral informant reports. A standard drink was defined as 14g of absolute ethanol content, which is equivalent to 12 ounces of beer, 1.5 ounces of hard liquor, or 5 ounces of wine.25 A heavy drinking day was defined as four or more drinks per day for women and five or more drinks per day for men.25 Drinking data were collected by experienced research personnel.
