is only predictive of substance use in the absence of externalizing symptoms (Dierker, Vesel, Sledjeski, Costello, & Perrine, 2007). For example, using an experience sampling method assessing daily negative affect and drinking in rising 9th graders over a 21 day period, we found that only those youth low in conduct problems were more likely to drink on days characterized by greater indicators of internalizing symptoms (Hussong, Gould, & Hersh, 2008).