.51) or in a set-based analysis limited to the 6 SNPs genotyped in the linkage disequilibrium block where interaction was detected in the CDP (p = .25). The 1 SNP yielding a significant interaction effect was located in the same block of the gene that yielded interaction effects in the CDP (position indicated on Fig. 1; that particular SNP was not genotyped in the CDP). The shape of the interaction for that SNP also suggested a crossover effect, though (as in the CDP findings for other SNPs) the genotypic means did not differ significantly at either end of the distribution (Fig. 3).
