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Chunk #50 — DISCUSSION

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Case-control association testing in the presence of unknown relationships.
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required to achieve an adequate correction [Marchini et al., 2004]. In general, multiallelic markers or haplotypes based on multiple SNPs can be considerably more informative than diallelic markers for association testing [Ott and Rabinowitz, 1997; Chapman and Wijsman, 1998]. For use with multiallelic markers or haplotype data, the easy extension and computation of the corrected χ2 test to the multiallelic situation is an advantage over GC.