Neuroimaging studies have found that integrity of white matter after TAI is correlated with injury severity and outcome.10–17 The neurocognitive impact of TAI has been documented by Kraus et al. 18 who found a reduction in the integrity of various white matter structures was associated with poorer performance on measures of attention, memory, and executive function. It is not yet known whether degree of white matter injury (i.e., structural integrity) is associated with impairment in neuronal (i.e., functional) activity between highly interconnected cortical regions.
