Chunk #3 — ONLINE METHODS — Imputation method with state space reduction

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Next-generation genotype imputation service and methods.

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yes

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In this reduced state space, we modify the Baum–Welch forward equations30 to obtain Lk(.) recursively for k = P + 1, P + 2, ...., Q. (2)Lk+1(Yi)=[[1−θk]Lk(Yi)+NiθkH∑j=1,…,ULk(Yi)]×P(Sk+1∣Yi)