These opposing findings further fuel the debate about how the dopamine system is altered during adolescence and mirror the seemingly contrasting findings of basal versus stimulated dopamine release in rodents. Given that there is relatively more evidence in support of the latter view, recent reviews on this topic suggest that the field has converged on the notion that, during adolescence, the striatal system is hyper-responsive to rewards and incentives (Ernst et al., 2009; Somerville et al., 2009). However, it is important to consider some plausible explanations for the disparate results.