A total of 1,210 individuals from the InCHIANTI study were genotyped using the Illumina Infinium HumanHap550 genotyping array13,14 . Individuals were pre-phased using autosomal SNPs after filtering out SNPs with MAF <1%, Hardy-Weinberg p-value <10-04, and missingness >1%. SNPs were also removed if they could not be remapped to the GRCh37 (hg19) human reference. This resulted in 483,991 SNPs available for pre-phasing. Phasing was performed locally using SHAPEIT2 10.