patients, how precisely and accurately these effects are quantified by clinicians, how practitioners use these estimates to optimize selections among antipsychotics for individual patients, and under what clinical care conditions antipsychotics are most effectively used with schizophrenic patients. CATIE investigated the symptomatic efficacies of antipsychotic drugs on the basis of group responses without consideration of how a practitioner would optimize drug management for an individual patient. As the resulting need for additional assumptions shows, group data and conditions divorced from the realities of patient care responsibilities do not predict outcome for a unique biological individual, the patient.
