We attempted to identify all cG×E studies published in the first decade (2000–2009) of cG×E research in psychiatry. We conducted searched using MEDLINE, PubMed, and Google Scholar, and we searched the reference sections of cG×E papers. Phenotypes in cG×E studies had to be DSM-IV diagnoses or closely related constructs (e.g., neuroticism). Only observational, as opposed to experimental, studies were included; pharmacogenetic studies were excluded. Studies were included only if there was variation across participants for phenotypic, genetic, and environmental variables; exposure-only designs were excluded.
