Chunk #42 — 4. DISCUSSION — 4.2 Considerations and Limitations

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Genetic etiology of the common liability to drug dependence: evidence of common and specific mechanisms for DSM-IV dependence symptoms.

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yes

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vary by DSM symptom and phenotype definition (Hardie et al., 2008; Lessov et al., 2004; Slutske et al., 1999). Limitations aside, this community-based study provides evidence for a genetically influenced substance dependence vulnerability underlying DSM-IV tobacco, alcohol, and cannabis dependence symptoms collected using an established structured interview.