At the age 15.5 in-person clinic, ALSPAC subjects were asked a series of questions about their alcohol consumption and associated alcohol-related symptoms/problems that correspond relatively well to the DSM-IV criteria for alcohol abuse and dependence. These items were extracted from the Semi-Structured Assessment of the Genetics of Alcoholism interview, developed by the Collaborative Study on the Genetics of Alcoholism (Bucholz et al., 1994; Hesselbrock et al., 1999). The alcohol items are listed in Table 2, along with mean scores for males and females.