For SLC30A8 rs13266634 data were also available from the deCODE investigation [21] and from another study by Sladek et al. [22]. Including these data, we got a random effects odds ratio of 1.15 (95% 1.10–1.19) with p = 3.5×10−13. Some low heterogeneity persisted (I2 = 21%). While SLC30A8 rs13266634 amply passed genome-wide significance when additional data were considered, the presence of between-study heterogeneity suggests the true culprit variant may still be elusive.
