rs2036527 genotype were 14.6 for AA, 13.5 for AG and 12.8 for GG, suggesting that there is an increase of less than one cigarette smoked per day for each copy of the A allele. This SNP accounted for approximately 0.20% of the phenotypic variance of CPD in our sample. This effect is similar to that reported for rs1051730, which is correlated with rs2036527, where each copy of the rs1051730 A allele corresponds to a approximately one CPD increase and accounts for 0.5% of the phenotypic variance in smoking quantity in populations of European ancestry.
