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Chunk #33 — Materials and Methods

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Rare variants create synthetic genome-wide associations.
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Genealogical trees were simulated using GENOME with an effective population size of 10,000 and a mutation rate of 10−8 in a 100-kb region. When recombination was simulated, 200 fragments of 500 bp each were used with recombination occurring between each fragment [38]. Trees were drawn using Dendroscope [39].