Chunk #52 — 4. PPARα and Hepatic Insulin Sensitivity

Source

Role of PPARα in Hepatic Carbohydrate Metabolism.

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Summarizing, during the fasted state, PPARα may have a stimulatory role on gluconeogenesis not only via direct gene induction or supporting glucocorticoid action (see Section 3.2), but also through impairment of insulin signaling, by inducing TRB3.