To date, relatively few studies have directly evaluated SRE-5 and SRE-T correlations across men and women in the same families or whether the correlates of those LR values are consistent from one generation to the next. Such evaluations are important because they could add to our understanding of whether SRE scores and correlates were limited to the original generation, perhaps reflecting the impact of the second parent’s genes and the differences across cohorts regarding drinking norms and practices (Seglem et al., 2016; White et al., 2015). In order to begin to evaluate aspects of the relative performance of SRE-5 and SRE-T across sexes and across generations, our group published data from the 25-year follow-up of SDPS families regarding drinking offspring at an average age of 20 years (Schuckit et al., 2007b; 2012a). Structural equation model evaluations of potential mediators of the relationship of SRE-based LR to later heavier drinking and alcohol problems were similar across generations (Schuckit et al., 2012a). However, the analyses were carried out when offspring were relatively young, did not include SRE-T scores, did not include direct
