targeted approach to the role of behavioral interventions in the treatment of smokers has been evaluated in the past (Fernander et al. 2006), but a targeted approach that considers racial and cultural differences that can lead to acceptability of and compliance with treatment for medical interventions has yet to be examined (Lillard et al. 2007; White et al. 2006). In a current study from a clinical treatment program, it was found that whereas gender differences existed in those enrolling in a formal treatment program, gender did not ultimately affect smoking abstinence at 6 months. It was hypothesized that this could possibly be due to individualization of the treatment program for each patient (Croghan et al. 2008b). An overall targeted approach in the medical management of tobacco dependence (behavioral and medical intervention) may also be the preferred approach in minority smokers.