Offspring of mothers smoking heavily during pregnancy more likely carried CHRNA3-rs1051730[A] than offspring of non-smoking mothers [OR(95%CI):1.39(1.04–1.87), P=0.03]. No differences in frequency of CHRNA3-rs1051730[A] were found when comparing offspring of mothers smoking 1–10 cigarettes/day with offspring of non-smoking mothers. No significant correlation was found between maternal smoking and genotype at TTC12-rs10502172[G] (see Supplement 1).
