There were negative genetic correlations between AUDIT total and AUDIT-C scores and obesity (rg = −0.16–0.17, p < 1.1 × 10−5), similar to previous reports regarding AUDIT total score (10) and alcohol consumption (9). In contrast, obesity was not significantly genetically correlated with AUDIT-P scores (rg = 0.01, p = 0.90). Similarly, HDL cholesterol and triglycerides were genetically correlated with AUDIT total score and AUDIT-C (rg = 0.19–22, p < 9.3 × 10−5, rg = −0.16, p < 1.0 × 10−4 respectively), but this association was not found for AUDIT-P (rg = 0.11, p = 2.2 × 10−2, rg = −0.03, p = 6.4 × 10−1). Obesity showed significantly different correlations with both AUDIT-P and AUDIT-C (Supplementary Table 6)
