Another predictor of future alcohol-related outcomes involves a person’s need for a higher number of drinks to achieve desired effects beginning early in their drinking career (Schuckit and Smith, 1996; Schuckit et al., 1997, 2007, 2008). This phenomenon, which might reflect lower alcohol sensitivity per drink and/or acute intrasession tolerance (Schuckit, 2018), has been known since the 1970’s as a low level of response, or low LR, to alcohol. Low LRs correlate with higher alcohol quantities per occasion even in relatively light drinkers as young as age 12 and before intersession tolerance was likely to have developed (Schuckit et al., 2008). In addition, among individuals who develop AUDs, a lower LR might also be associated with a greater chance of abstinence or low-risk drinking recoveries (Gonçalves et al., 2017; Trim et al., 2013). This might reflect the absence of a strong relationship between a lower LR and other risk factors cited as increasing both the risk for and severity of AUDs, including high levels of impulsivity and sensation seeking that might impact on a more severe AUD course (Fein et
