ALDH7A1 is duplicated in the macaque. The ALDH7A1P5 duplication is located on Chr 14 and contains the complete ALDH7A1 coding sequence; however, the sequence lacks any intronic regions, suggesting a reverse transcriptase-mediated duplication event. Furthermore, this gene has a Ka/Ks score of 1.289, indicating a lack of selective pressure to conserve this gene. This provides further evidence that ALDH7A1P5 does not code for a functional protein.
