Our review focuses on studies of uncomplicated alcoholism as distinguished from special cases of alcohol-related disorders such as Korsakoff’s syndrome (Oscar-Berman, 2012), alcohol dementia (Brust, 2010; Vetreno et al., 2011), and Marchiafava-Bignami disease (Kim et al., 2007). Our review excludes studies of adolescent drinkers, as well as research investigating binge drinking, the episodic heavy consumption of alcohol. Additionally, although studies using acute alcohol administration have direct applicability to driving situations, work-related hazards, and other societally relevant concerns, here we consider residual neuropsychological functions associated with long-term chronic alcoholism.