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Chunk #5 — Materials and Methods — Measures — Covariates and Measures for Robustness and Sensitivity Analyses.

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Sibling comparisons elucidate the associations between educational attainment polygenic scores and alcohol, nicotine and cannabis.
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We included sex, age at last interview, cohort (indexed using three dummy-coded variables derived from participant year of birth: [1896–1930) set as reference; [1930–1950); [1950–1970); [1970–2010)) and the first two principal components for genetic ancestry in all analyses.