distance of two regions for 93% of samples. The accuracy increased to 58% (87% to within one region, 97% to within two regions) when restricting to the 98 (of 250) samples with at least 16 of 32 ancestors from a single region. Our analyses demonstrate that dense genotype data can be used to distinguish, and to some extent predict, the regional geographic ancestry of individuals within Iceland. We note that a correlation between geography and genetic ancestry has also been observed in other parts of Europe [19]–[22].