Our GWA study of BD provides some support for previous findings that variation in ANK3 and at 15q14 influence BD susceptibility. In addition, regions containing NAP5, NTRK2, SLITRK2, and ROR1 are worthy of follow-up studies. As all of these associated SNPs and regions have small effect size, it is likely, however, that the majority of the genetic variations that influence BD remain yet to be discovered.
