Our VS reactivity paradigm consists of a number guessing task wherein participants receive predominantly positive feedback (80% correct guess), predominantly negative feedback (20% correct guess), or no feedback. There are three pseudorandomly presented blocks of each condition. Participants are unaware of the fixed outcome probabilities associated with each block and are led to believe their performance will determine a net monetary gain at the end of the scanning session. Instead, all participants receive $10. Here we focus on differential VS reactivity from Positive > Negative Feedback blocks. BOLD fMRI acquisition parameters, preprocessing and analytic techniques are described in detail in Supplementary Methods.
